PPAR modulation of kinase-linked receptor signaling in physiology and disease.
نویسندگان
چکیده
Kinase-linked receptors and nuclear receptors connect external cues to gene transcription. Among nuclear receptors, peroxisome proliferator-activated receptors (PPARs) are of special interest in relation to widespread human diseases. Mapping out connections between PPARs and kinase-linked receptor signaling is central to better understand physiological and pathophysiological processes and to better define therapeutic strategies. This is the aim of the present review.
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عنوان ژورنال:
- Physiology
دوره 25 3 شماره
صفحات -
تاریخ انتشار 2010